Tranexamic Acid (500 mg)
Trace tablet is used to treat bleeding by preventing rapid rupture of clots, such conditions are tooth extraction, heavy periods, useless uterine bleeding, hemorrhage, and any oral, postulate, or bladder surgery. This helps prevent excessive loss of blood and enhances the healing process.
Tranexamic acid (sometimes short for txa) is a medication that controls bleeding. It helps to clot your blood and is used for hemorrhage and heavy periods. If you are removing a tooth, using a tranexamic acid mouthwash can help prevent bleeding.
Mechanism of Action
Tranexamic acid exerts an antifibrinolytic effect by forming a reversible complex with plasminogen through the lysine binding site of fibrin and thereby displacing plasminogen from the fibrin surface; Inhibiting the binding of plasmin to fibrinogen or fibrin monomers. It inhibits the activation of plasminogen (ie the formation of plasmin). It also acts as a weak non-competitive inhibitor of plasmin and blocks its action on fibrin.
1. Surgical procedures 2. Menorrhagia 3. Metorrhea 4. Postpartum hemorrhage 5. Bleeding after miscarriage 6. Bleeding due to insertion of a contraceptive device. 7. Foot extracts and bleeding in processes of other molecules 8. Penistasis 9. Hemopathies 10. Bleeding. Prostatectomy 12. Tonsillectomy 13. Fibrinolysis 14. Trauma 15. Orthopedic Surgery 16. Cardiovascular Surgery.
Absorption: About 40% is absorbed orally. Distribution: Widely distributed in the body. Excretion: Excreted mainly as unchanged drug.
Drug interactions can change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription / nonprescription drugs and herbal products) and share them with your doctor and pharmacist. Do not start, stop, or change the dose of any medicine without your doctor’s approval.
Some products that may interact with this drug include: “blood thinners” (anticoagulants such as warfarin, heparin), drugs that inhibit bleeding (including Factor IX complex, anti-inhibitor coagulant constants), estrogen, Hormonal birth control (eg pills patch, ring), tibolone, tretinoin.
1. Extremely severe I.V. Administration 2. Dose adjustment is necessary for renal weakness.
Tranexamic acid tablets are usually taken 3 times a day for a maximum of 4 days. As soon as your period starts you start taking pills. Tranexamic acid pills are not a form of contraception and will not affect your chances of getting pregnant.
Oral: 3 to 4 g / day in 3 to 4 divided doses or 15 to 25 mg / kg body WT. 3 to 4 times daily. I.V .: 1.5 to 3 g / day in 3 divided doses or 10 to 15mg / kg body wt. 3 times daily. Slow-administered IV As an injection or continuous infusion; At the rate of 25 to 50mg / kg / day.
Duration of action:
Then the concentration decreases to the 6th hour. The elimination half-life is approximately 3 hours.
1. Nausea 2.Diarrhoea 3. Gastrointestinal problems 4. Headache 5. Hypotension 6. Injection 7. Thrombophlebitis via intravenous injection
Store below 25 degrees C and there is electricity from light. Keep out of reach of children.
Treatment is helpful and symptomatic. Remove the drug from the body by activated charcoal to reduce induced excretion, gastric lavage, and absorption. Maintain an adequate diet with the help of fluids and diuretics.
Thromboembolic disorder 2. Subarachnoid hemorrhage 3. Excessive upper urinary tract bleeding 4. Color vision disorder 5. Thrombophlebitis 6. Hypnotic impaired 7.Several renal impairments.
Caution is advised in the treatment of people with massive hematuria from the upper urinary tract, especially in hemophilia, as there have been some cases of ureter obstruction.
It may not be used when intravascular coagulation diffusion is being performed.
A dose reduction is recommended in patients with increased blood levels and renal insufficiency.
In those patients requiring long-term administration of tranexamic acids, such as those with hereditary angioneurotic edema, routine eye examinations (such as visual acuity, slit lamp, intraocular pressure, visual field) and liver function tests should be performed. Patients who experience visual disturbances should be removed from treatment.
Breast Feeding: Use with caution
Tranexamic acid in breast milk contains about one hundred grams of breast milk. An antifibrinolytic effect is unlikely in the infant.
Use with caution