CYS – 10

CYS 10

Serratiopeptidase (10 mg)

CYS 10mg Tablet is used in the treatment of pain and inflammation. It helps in relieving pain and inflammation in the postoperative wound and inflammatory diseases. Serratiopeptidase or Serrapeptase is a protein (proteolytic) enzyme isolated from the non-pathogenic Enterobacteria Serratia E15 found in silkworms. Serratiopeptidase is a proteolytic enzyme used to reduce inflammation, has antidemic, analgesic, fibrinolytic, and casinoolytic properties.

Mechanism of Action

This anti-inflammatory proteolytic enzyme binds to alpha-2-macroglobulin in the blood, which helps mask its antigenicity. It is then slowly transferred to the site of inflammation. Serratiopeptidase hydrolyzes bradykinin, histamine, serotonin which is responsible for edema. It reduces inflammation, improves microcirculation and expulsion of sputum. Due to this action, serratiopeptidase has anti-inflammatory, antilipidemic, and fibrinolytic activity and acts rapidly on local inflammation.

Indications

 1. Antiinflammatory 2. Antiswelling 3. Anti- rheumatoid 4. To promote the transfer of antibiotics to the site of action 5. To promote lysis and discharge of sputum and pus 6. Bronchitis 7. Fibrocystic breast swelling 8. Sinusitis 9. Cough 10. Laryngitis 11. Fibromyalgia 12. Emphysema 13. Gout

Pharmacokinetic Properties:

Orally absorbed. In the case of bowel coated tablets, there is absorption in the intestine. After absorption, it enters the bloodstream directly. It is excreted through urine and bile.

Drug-Drug interactions:

not reported.

Precautions:

In patients with renal failure or liver failure, when taking any anti-inflammatory agent on an empty stomach, the physician should alert the patient to abdominal pain. Such enzyme preparations should be used in patients with gastritis and a history of gastric ulcers, as well as in patients taking blood thinners.

Breastfeeding:

Tell your doctor if you are breastfeeding, as there is no information available about the use of this medicine. Your doctor will tell you about the use of this medicine after assessing the benefits over the risks.

Fertility:

information not available.

Dosage:

Adults-5 to 10mg tab every 3 times daily. 10- 30 mg tab /day.

Duration of action:

8 to 10 hrs

Adverse Reaction:

1. Hypersensitivity 2. Anorexia 3. Gastric discomfort 4. Nausea 5. Vomiting 6. Epistaxis 7. Diarrhea 8. Skin rash

Storage:

Store below 25 degrees Celsius, protect from light and moisture.

Overdosage:

Give supportive measures and symptomatic treatment.

Contraindictions:

Hypersensitivity to this drug 2. Blood coagulation disorder

Warnings: 

Caution should be exercised in patients with a history of liver or kidney disease during pregnancy and breastfeeding.

Pregnancy

Contraindicated

Breast Feeding

Contraindicated