CEFAR- 500 MG
Cefuroxime Axetil (500 mg)
cefuroxime is also known as Ceftin or cephalosporin antibiotic. It is available as a generic drug and used to treat only bacterial infections such as skin, middle ear infections, tonsillitis, throat infections, laryngitis, bronchitis, pneumonia, urinary tract infections, and gonorrhea. It will not work for viral infection.
Mechanism of Action
To reduce the growth of CEFAR-500 drug-resistant bacteria and to maintain the effectiveness of CEFAR-500 and other antibacterial drugs. After oral administration Cefuroxime extracts are absorbed from the gastrointestinal tract and safely hydrolyzed by non-specific astrogases in the intestinal mucosa and transported to a safe place in the blood. Cefuroxime is subsequently distributed via extracellular fluids. Acetyl mutations are metabolized to acetaldehyde and acetic acid.
About 50% of serum cefuroxime protein is bound to the serum. Pharmacokinetic parameters of dose cefuroxime axetil –CEFAR-500mg – peak plasma concentration – 7, peak plasma concentration-time – 3 (hr), mean half-life (hr) – 1.2 and AUC-27 mcg-hr. me. CEFAR-500 is unchanged in the urine in adults. About 50% of the administered dose is urine recovered within 12 hours.
Antacids -containing aluminum or magnesium, histamine2-receptor antagonists: increased cefuroxime absorption. Concomitant administration of probenecid with CEFAR-500 tablets increases the area under the serum versus the time curve by 50%. Peak serum cefuroxime concentrations after 1.5 g single dose are higher when taken with 1 gram probenecid (mean = 14.8 mcg / ml) compared to probenecid (mean = 14.2 mcg / ml).
Root Initiation PeakDuration
P.O. Unknown 2 hours 8-12 hours
I.V., I.M. Infusion end infusion 6–12 hr
Before taking Cefuroxime, tell your doctor or pharmacist if you are allergic to it; Or penicillin or other cephalosporin antibiotics (eg, cephalexin); Or if you have any other allergies. This product may contain inactive ingredients, which may cause allergies or other problems. Talk to your pharmacist for more details.
Before using this medicine, tell your doctor or pharmacist your medical history, specifically: kidney disease, intestinal disease (colitis), liver disease, poor nutrition.
This drug may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or dry. Do not drive, use machinery, or do anything that requires vigilance until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
Live bacterial vaccines (such as typhoid vaccine) may not work due to cefuroxime. Do not take any vaccinations/vaccinations while using this medicine unless your doctor tells you to.
There are no data on the effects of cefuroxime axetil on fertility in humans. Reproductive studies in animals have not shown any effect on fertility. There have been no studies on the effects on the ability to run and use machines.
The adult dose may range from 125 to 500 mg, taken twice a day. A dose of 1 gram is used to treat gonorrhea. Children under 12 years of age can safely take this medicine, usually in two daily doses of 125 or 250 mg per dose.
CEFAR-500 works the fastest when taken on an empty stomach, but it can be taken with food if the stomach is upset. For children, tablets can be crushed and added to food.
Duration of action:
Peak concentrations are reached one hour after dosing; however, it may take up to 48 hours for symptoms related to the infection to dissipate.
CNS headache, hyperactivity, hypertonia, seizures.
GI nausea, vomiting, diarrhea, abdominal pain, dyspepsia, pseudomembranulitis
Gujrat hematuria, vaginal candidiasis, glial dysfunction, acute penis abscess.
Hematologic Hemolytic Animation, Aplastic Animation, Hemorrhage
Hepatic liver disease.
Skin Toxic Epidermal Necrolysis, Erythema Multi-Performance, Stevens-Jonson Hybrid
Other active disability, drug fue, superinfection, and anaphylaxis.
Store in a cool and dry place. Protect from light and moisture.
Any medication taken in excess can have serious consequences. An overdose with cephalosporin antibiotics can cause brain irritation, which can cause convulsions. If you suspect an overdose, seek medical attention immediately.
Hypersensitivity to cephalosporin or penicillin • Carnitine deficiency.
If you have ever had a severe allergic reaction to any type of cephalosporin antibiotic (Omnicef, Keflex, and others), you should not use ciproxime.
Pregnancy: Use With Caution
Children: Use With Caution
Breastfeeding: Use With Caution